The use of MCDL can improve the patient's response to gonadotropin therapy. 5 retrieved, 3 fertilized, 2 transferred on day 3, none froze, BFN. With IVF#2, we did MDL. 2TFR'ed. Finally some (tough) answers. Most recent cycle was most devastating: 3 eggs fertilized, they transferred all 3 on day 3 and then I got my period 3 days before my blooddraw. Woot woot!! I wont be using birth control, just starting lupron a week after ovulation. Er 5: oct 2020 - same protocol as er 4- 4 mature eggs, no blasts Er 6- jan 2021- GH and estrace priming for 4 days. Thanks! 0000001040 00000 n . Well, the answer is that I did a LOT! And Yay for no BCP, I hate that stuff, I've done all the different methods with the exception of EPP. A few days after stopping the BCPs, she will have a period and she will then start taking FSH or hMG daily until her largest follicles are mature. Just checking in to see how you did with the flare protocol. Some of these involve the use of oral medications, such as Clomid or Femara in addition to gonadotropins. Lupron, a GnRH agonist, is one of the best known and most hated of IVF treatment injectable fertility drugs. If this next one doesnt work, perhaps ask for a pregnancy loss bloodwork panel. But ER 1 and 2 antagonist, next antagonist +HGH = 0 blasts ER 3 MDLF = 2 untested day 6, 5 AA.. but ER3 was 6 months after ER1 so not sure if it was supplements/lifestyle changes which did the trick. I'm super excited for you, yay!!! Wondering if anyone with diminished ovarian reserve has had success with IVF stimulation during the luteal phase vs. the follicular phase? GnRH agonists like Lupron are primarily used for the treatment of endometriosis and fibroids. Hopefully they know what they're doing! However other had mature egg and we did Icsi by it didn't grow from there. Even though my eggs were older as I was 37 at the time, versus 35 when I started, we transferred 2 and were successful with a singleton. Even though I did not get pregnant - this protocol has worked the best for me. If nothing else were done, the patient would ovulate approximately 36-42 hours after her hCG injection. It is quality that matters. You Will Mother. I was diagnosed with high FSH (16). It can prolong the survival of sperm by depositing them directly into the uterus and avoiding the hostile environment of the vagina. What now - IUI, Adoption, Donor Eggs or Donor Embryos, Retire Early?! October '13 Started BCP for December IVF. 16dp5dt. He takes my input and works with me. Now is the perfect time to start your Baby Registry! The educational health content on What To Expect is reviewed by our medical review board and team of experts to be up-to-date and in line with the latest evidence-based medical information and accepted health guidelines, including the medically reviewed What to Expect books by Heidi Murkoff. Estrogen Primed Microdose Lupron Flare Protocol. I'm about to start a microdose lupron flare cycle tomorrow! Microdose Lupron Flare Protocol. I'd love to hear any success stories from people with a similar history to mine. But after the estrogen my 3 follilces seemed to be more closely matched in size. Short Lupron (Microdose or Flare) Protocol for IVF. Also plenty of cases in this board and other places where women only have 4 eggs retrieved and get a normal. Now.our concern is premature ovulation and he is monitoring me more for that. I would like to know if any has been on the EPP/ MDL protocol ? Fraternal girls born Dec 2010 2011 Dec-Natural BFP M/C at 8.5 wks 2012 Dec-Natural BFP . After another failed IVF attempt using the Microdose Lupron protocol, my RE now suggests the Estrogen Patch protocol as I am a poor responder. (ex. IVF Cycle #5 | Microdose Lupron Flare Protocol | Low AMH 2,095 views Feb 5, 2022 64 Dislike Share Tiana Smith 1.24K subscribers Hello All! Had 19 follicles on my baseline, which was really good for me, but I ended up with 4 large follicles . As I have been trying naturally as well there is a chance I could be pregnant. Completed is probably not the right word because we have not yet gotten to transfer a single embryo. hi, I did it at age 38. This protocol is our favorite for patients with care low ovarian reserve or chancellor who were poor quality after taking BCP. We learned, after mont, Hello This community is sponsored by RESOLVE: The National Infertility Association, an Inspire trusted partner. IVF # 1 (flare protocol) Cancelled (poor response) 2010 IVF # 1 (2nd attempt)-microdose flare/estrogen priming BFP! (My clinic requires ICSI and PGS testing for all patients). My dr wants the lining to be between 8-12. I have DOR (My AMH was 0.38 and 0.27 in 2016, but somehow it increased to 1.36 in Jan 2017). I understand the fear. He had a vasectomy after his second child. How do you recover from a failed IVF? 0000009011 00000 n Microdose lupron protocol This is a very popular protocol for low responders with diminished ovarian reserve. This is witho. I am starting on my fourth mini stimulation IVF and am looking for any insight into my situation, words of encouragement of those in a similar position or anyone that has experience with the Estrogen Priming Protocol. When I stimmed, this is also the thickest I ever was. It's not your first rodeo here." So it seems to me it's time to change the protocol, do another cycle and gather more inform, HelloHave been reading the boards, but have never posted. Lupron Trigger During Stimulated IVF Cycles. San Antonio, TX 78258, 7629 S Staples Ste 106A The first one I did long lupron and produced 14 eggs, 13 fertilized, 9 made it to day 3, we transferred 3 that day (2 8cell B and 1 10cell B) and then none of the other 6 made to blast. More importantly, do you think these estrogen spikes and/or the overly aggressive protocol damaged my . I feel like this entire experience has been a series of problem found, problem solved, and another problem found. I have a normal AMH for my age but I've read this protocol is for DOR or poor responders. This educational content is not medical or diagnostic advice. They are giving three more days on stimming before making the call. However, I think I am in the minority as clearly it works incredibly well for some. I dont want to keep trying protocols and not succeeding. Others involve newer supplements such as DHEA, and still others involve the use of injectable medications such as growth hormone. 150 iu follistim and 75 iu menopure didn't work either. In the regular IVF protocol, Lupron and BCP are used for at least 2 weeks before ovarian stimulation. Previous studies comparing E2 priming and leuprolide flare IVF protocols report that E2 priming protocols result in longer cycles and higher total gonadotropin dose with similar oocyte yield, fertilization, and pregnancy rates; though, one report suggests a trend toward higher quality embryos in E2 priming cycles. I am going in for my 4th IUI in what was supposed to be an IVF cycle. I will access my frozen eggs in.june hopefully. Both hCG and Lupron effectively trigger maturation, (necessary for IVF success), but Lupron is better tolerated. I went through Dr. Geoffrey sher from SIRM, who mentioned that a high LH surge initially with lupron flare or clomid or menopur can cause low quality. I had my first cycle canceled due to poor response to stims and ovulating through the lup.. My next cycle will be with EPP no BCP, but keeping the same Lup. it helps prevent ovulation - 1/8 tablet or 1/4 tablet, inserted vaginally, overnight (and i use a special silicone plug, AND, /the inner plunger from a tampon applicator/, to push the plug deeper or else it slides out if you need to use the loo, during the night. Thoughts on different protocols? Once down regulation was obtained, the lupron dose was decreased to 0.125 mg daily and gonadotropin stimulation was initiated. I took BCP for 3 weeks. She has already been prescribing me an aggressive protocol (microdose Lu, So a little bit about me. 1. Thanks! My first two cycles yielded one lousy frozen each. I know everyone's situation is completely different, and we all respond differently to the meds, but I just thought I would ask. If you feel a message or content violates these standards and would like to request its removal please submit the following information and our moderating team will respond shortly. The sad part of the story is that my dr was so excited and confident I would get pregnant he transfered In all 3 fresh cycle. While many studies to evaluate the effectiveness of these additional medications have been conducted, there are unfortunately very few definitive conclusions that have been reached. An EPP for you. It seems to be . Have done 3 IUI's - 2 w. clomid and 1 with Gonal - F. I had a hyrdo on my left tube which had been removed and no left ovary to be found :( But I do have a good right tube & ovary. thanks! I see! What I have seen in my years of fertility groups for women with DOR is that it seems many of our bodies like femara. First time posting here. Beta2 9/12: 378! 0000009528 00000 n This is primarily because of the unpleasant side effects: mood swings, headaches, and hot flashes. Your post will be hidden and deleted by moderators. Long time reader, first time poster. Three days following the last OCP, lupron 20 mcg b.i.d. LUPRON (leuprolide acetate): If your baseline ultrasound shows that your ovaries are free of large cysts and your estradiol level is adequately low, you will begin Lupron injections to initially stimulate your ovaries, to suppress your natural cycle. %%EOF EPP with CCRM has been my best cycle yet in regards to embryo quantity and quality! So for this 3rd FET my dr has added in estrogen injections. After taking a break from infertility to regroup (in which I drank approximately 20 drinks in one evening and was hungover until 7pm the following day, oops), we had out WTF conf call with our RE to go over what happened last cycle/ get some closure/ get a game plan for next time. Hi! NT- all looks good. Well, my 4 long months of waiting to cycle again are finally over, and I am starting IVF #4 on Friday. MENTS: This time around I did estrogen priming and the results of my day 5 ultrasound were disappointing (8 follicles, with an E2 level of 98.6) and now at day 7 they are worse (2 of the smaller follicles haven't budged in size so only 6 seem to be in the game but 3 are leading). You start today right?!? Instead we are doing estrogen priming followed by microdose lupron. This typically takes 8-12 days, during which time the stimulation is monitored using a combination of vaginal ultrasound and a blood estrogen level approximately every 2-3 days. I performed poorly with estrogen priming, so we are taking it out now.hsve you started stim? I like my current doctor. I'm nervous that round 2 will go the same way as round 1. 0000005824 00000 n However, that information will still be included in details such as numbers of replies. Reproductive medicine fertility society of . So I know that you begin with birth control (but I, I've had one unsuccessful IVF and one that had such a poor response we turned it into an IUI instead. The nurses at my clinic are suggesting the following schedule: Lupron Depot is used in women to treat symptoms of endometriosis (overgrowth of uterine lining outside of the uterus) or uterine fibroids. I often find myself feeling really hopeless. Austin, TX 78749, 705 Generations Dr, Suite 102 I'm doing it now the patch seems to be less obnoxious than the pill, but I'd like to hear about peoples experiences. Approximately fifteen years ago, a different type of GnRH analog was developed. This is my second attempt at ivf my first ivf was unsuccessful no embryos made it to day 5. IVF#4 (Dec2013/Jan 2014): Microdose flare+Saizen+testosterone 4 eggs retrieved, all mature and fertilized by ICSI, ET of 1 6-cell embryo an 1 8-cell embryo graded 2 and 3. 6500 N. Mopac (Loop 1) Expressway Building 1, MENTS I married at 39 and got pregnant naturally a year later, then miscarried. We are all intent upon choosing the absolute best protocol for your individual circumstances in order to optimize the number of retrieved eggs, maximize the fertilization rate, and provide you with the greatest possible chance for a healthy pregnancy. What should we try that we haven't already? That cycle we got 9 retrieved, 7 fertilized and 5 good quality blasts and a successful FET a couple of months later. (Intralipids and Lovenox). At my age of 42, I am praying for more than 7 or 8 eggs and better quality for PGS testing. I did this protocol for my cycle. Dont get discouraged. The LDL protocol was initiated with late luteal lupron (0.25 mg daily). In addition, your chance of developing ovarian hyperstimulation syndrome is less with GnRH antagonist protocols. Five days before her last BCP, she will start Lupron. So if u want to give it one more try isay go for it. Group Leaders communicate with staff moderators and escalate potential violations for review, but they dont moderate discussions. Infertility doesn't go away after the first positive test. 16 22 Er 6- jan 2021- GH and estrace priming for 4 days. Flare, or Micro-dose Lupron Protocol: In women who are of advanced maternal age, or for those who've had a poor response to other protocols, your fertility specialist may recommend this protocol, involving a lower dose of Lupron which will be started at the same time as the FSH injections. If we believe that a particular patient will not respond well to stimulation medications, either because she is older, she has diminished ovarian reserve, or she has had previous ovarian surgery, we will frequently use our poor responder protocol. So I don't have anything to add but I'll be watching you;-). I have my egg retrieval on Thursday & was curious if anyone had similar timing & wanted to be my buddy. 28 years old, first IVF cycle cancelled?! I definitely dont feel like myself but not as bloated yet. BCP's-Re gave me a pack free Estrogen priming and the agonist-antagonist conversion protocol is at least as successful as the microdose flare protocol based on medical data. I'm 42 y/o and had my 2nd egg retrieval on 4/16. MENTS..I am now 17 wks pg from that cycle. --- EDD 4/5/15, "Everything will be alright in the end. More than 7 or 8 eggs and better quality for PGS testing for all patients ) 3 fertilized 2! I 'm 42 y/o and had my 2nd egg retrieval on Thursday was. N microdose lupron flare cycle tomorrow # x27 ; s response to gonadotropin therapy now 17 wks pg that... A microdose lupron flare cycle tomorrow and another problem found, problem,. High FSH ( 16 ) 0.38 and 0.27 in 2016, but I 'll be watching you -... In details such as numbers of replies was diagnosed with high FSH ( 16 ) wont be using control! 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( flare protocol ) Cancelled ( poor response ) 2010 IVF # on!, Hello this community is sponsored by RESOLVE: the National Infertility Association, Inspire! Of fertility groups for women with DOR is that I did a LOT what now - IUI Adoption! Success stories from people with a similar history to mine stimulation during the luteal phase vs. the follicular phase as! You ; - ) and not succeeding added in estrogen injections word because we have yet... Decreased to 0.125 mg daily and gonadotropin stimulation was initiated did not get pregnant this... Donor eggs or Donor Embryos, Retire Early? so we are estrogen. At 8.5 wks 2012 Dec-Natural BFP M/C at 8.5 wks 2012 Dec-Natural BFP M/C 8.5!
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